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Nitric oxide produces HLA-G nitration and induces metalloprotease-dependent shedding creating a tolerogenic milieu

Human leucocyte antigen G (HLA-G) is a tolerogenic molecule that protects the fetus from maternal immune attack, may favour tumoral immunoescape and is up-regulated in viral and inflammatory diseases. The aim of this work was to discover if nitric oxide (NO) could affect HLA-G expression or function...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Díaz-Lagares, Angel, Alegre, Estibaliz, LeMaoult, Joel, Carosella, Edgardo D, González, Álvaro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669824/
https://ncbi.nlm.nih.gov/pubmed/18764882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02911.x
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