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New insights into intra- and intermolecular interactions of immunoglobulins: crystal structure of mouse IgG2b-Fc at 2·1-Å resolution

The structure of the Fc fragment of monoclonal antibody IgG2b from hybridom M75 of Mus musculus has been determined by single crystal X-ray diffraction. This is the first report of the structure of the murine immunoglobulin isotype IgG2b. The structure refined at 2·1 Å resolution provides more detai...

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Main Authors: Kolenko, Petr, Dohnálek, Jan, Dušková, Jarmila, Skálová, Tereza, Collard, Renata, Hašek, Jindřich
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669818/
https://ncbi.nlm.nih.gov/pubmed/18783468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02904.x
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