Staged stromal extracellular 3D matrices differentially regulate breast cancer cell responses through PI3K and beta1-integrins

BACKGROUND: Interactions between cancer cells and stroma are critical for growth and invasiveness of epithelial tumors. The biochemical mechanisms behind tumor-stromal interactions leading to increased invasiveness and metastasis are mostly unknown. The goal of this study was to analyze the direct e...

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Main Authors: Castelló-Cros, Remedios, Khan, David R, Simons, Jeffrey, Valianou, Matthildi, Cukierman, Edna
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669806/
https://ncbi.nlm.nih.gov/pubmed/19323811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-94
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