Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol ε and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors

BACKGROUND: Evolution of DNA polymerases, the key enzymes of DNA replication and repair, is central to any reconstruction of the history of cellular life. However, the details of the evolutionary relationships between DNA polymerases of archaea and eukaryotes remain unresolved. RESULTS: We performed...

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Autors principals: Tahirov, Tahir H, Makarova, Kira S, Rogozin, Igor B, Pavlov, Youri I, Koonin, Eugene V
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669801/
https://ncbi.nlm.nih.gov/pubmed/19296856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-4-11
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