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Gold(I)-Catalyzed Coupling Reactions for the Synthesis of Diverse Small Molecules Using the Build/Couple/Pair Strategy

[Image: see text] The build/couple/pair strategy has yielded small molecules with stereochemical and skeletal diversity by using short reaction sequences. Subsequent screening has shown that these compounds can achieve biological tasks considered challenging if not impossible (‘undruggable’) for sma...

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Main Authors: Luo, Tuoping, Schreiber, Stuart L.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2009
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669759/
https://ncbi.nlm.nih.gov/pubmed/19331418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja900414s
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