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Posttranslational regulation of TPH1 is responsible for the nightly surge of 5-HT output in the rat pineal gland
Serotonin (5-hydroxytryptamine, 5-HT), a precursor for melatonin production, is produced abundantly in the pineal gland of all vertebrate animals. The synthesis of 5-HT in the pineal gland is rate limited by tryptophan hydroxylase 1 (TPH1) whose activity displays a twofold increase at night. Earlier...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669754/ https://ncbi.nlm.nih.gov/pubmed/18705647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-079X.2008.00627.x |
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