5,7-dihydroxy-3,4,6-trimethoxyflavone inhibits the inflammatory effects induced by Bacteroides fragilis enterotoxin via dissociating the complex of heat shock protein 90 and IκBα and IκB kinase-γ in intestinal epithelial cell culture

Enterotoxin produced by enterotoxigenic Bacteroides fragilis (BFT) has been associated with mucosal inflammation and diarrhoeal diseases. In this study, the anti-inflammatory molecular mechanism of 5,7-dihydroxy-3,4,6-trimethoxyflavone (eupatilin) was characterized in an HT-29 intestinal epithelial...

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Detalhes bibliográficos
Main Authors: Kim, J M, Lee, D H, Kim, J S, Lee, J Y, Park, H-G, Kim, Y-J, Oh, Y-K, Jung, H C, Kim, S I
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669531/
https://ncbi.nlm.nih.gov/pubmed/19220840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03849.x
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