T cell senescence and contraction of T cell repertoire diversity in patients with chronic obstructive pulmonary disease

Pathogenetic mechanisms leading to chronic obstructive pulmonary disease (COPD) remain poorly understood. Because clonogenic T cells (CD4(+)CD28(null)) were shown to be increased in autoimmune diseases we hypothesized that CD4(+)CD28(null) T cells play a role in COPD. Here we describe that enhanced...

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Detaylı Bibliyografya
Asıl Yazarlar: Lambers, C, Hacker, S, Posch, M, Hoetzenecker, K, Pollreisz, A, Lichtenauer, M, Klepetko, W, Jan Ankersmit, H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2009
Konular:
Inflammation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669523/
https://ncbi.nlm.nih.gov/pubmed/19220836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03835.x
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