Evaluation of Strong Cation Exchange versus Isoelectric Focusing of Peptides for Multidimensional Liquid Chromatography-Tandem Mass Spectrometry

Shotgun proteome analysis platforms based on multidimensional liquid chromatography-tandem mass spectrometry (LC-MS/MS) provide a powerful means to discover biomarker candidates in tissue specimens. Analysis platforms must balance sensitivity for peptide detection, reproducibility of detected peptid...

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Auteurs principaux: Slebos, Robbert J.C., Brock, Jonathan W.C., Winters, Nancy F., Stuart, Sarah R., Martinez, Misti A., Li, Ming, Chambers, Mathew C., Zimmerman, Lisa J., Ham, Amy J., Tabb, David L., Liebler, Daniel C.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669493/
https://ncbi.nlm.nih.gov/pubmed/18939861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr8004666
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