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In silico prioritisation of candidate genes for prokaryotic gene function discovery: an application of phylogenetic profiles

BACKGROUND: In silico candidate gene prioritisation (CGP) aids the discovery of gene functions by ranking genes according to an objective relevance score. While several CGP methods have been described for identifying human disease genes, corresponding methods for prokaryotic gene function discovery...

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Detalhes bibliográficos
Main Authors: Lin, Frank PY, Coiera, Enrico, Lan, Ruiting, Sintchenko, Vitali
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669486/
https://ncbi.nlm.nih.gov/pubmed/19292914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-86
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