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Conversion of NO(2) to NO by reduced coenzyme F(420) protects mycobacteria from nitrosative damage

In mycobacteria, F(420), a deazaflavin derivative, acts as a hydride transfer coenzyme for an F(420)-specific glucose-6-phosphate dehydrogenase (Fgd). Physiologically relevant reactions in the mycobacteria that use Fgd-generated reduced F(420) (F(420)H(2)) are unknown. In this work, F(420)H(2) was f...

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Detalhes bibliográficos
Main Authors: Purwantini, Endang, Mukhopadhyay, Biswarup
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669391/
https://ncbi.nlm.nih.gov/pubmed/19325122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812883106
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