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Metronomic chemotherapy: changing the paradigm that more is better

The introduction of the “maximum tolerated dose” in usual treatment protocols (and its concomitant overt toxicity) made necessary the imposition of rest periods between cycles of therapy—a practice that not only involves re-growth of tumour cells, but also growth of selected clones resistant to the...

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Autori principali: Scharovsky, O.G., Mainetti, L.E., Rozados, V.R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Multimed Inc. 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669231/
https://ncbi.nlm.nih.gov/pubmed/19370174
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