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HacA-Dependent Transcriptional Switch Releases hacA mRNA from a Translational Block upon Endoplasmic Reticulum Stress

Activation of the unfolded protein response (UPR) in eukaryotes involves the splicing of an unconventional intron from the mRNA encoding the transcriptional activator of the pathway. In Saccharomyces cerevisiae a 252-nucleotide (nt) unconventional intron is spliced out of the transcript of HAC1, cha...

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Detalhes bibliográficos
Main Authors: Mulder, Harm J., Nikolaev, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669205/
https://ncbi.nlm.nih.gov/pubmed/19181870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00131-08
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