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T-cell modulation combined with intratumoral CpG cures lymphoma in a mouse model without the need for chemotherapy

We have previously shown that intratumoral injection of CpG oligodeoxynucleotide plus systemic chemotherapy can induce a T-cell immune response against lymphoma and serve as a therapeutic vaccine to cure tumors in a murine model. Here, we demonstrate that antibody-mediated modulation of T cells incr...

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Hlavní autoři: Houot, Roch, Levy, Ronald
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668854/
https://ncbi.nlm.nih.gov/pubmed/18941113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-170274
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