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Evolution of Mutation Rates: Phylogenomic Analysis of the Photolyase/Cryptochrome Family

Photoreactivation, one of the first DNA repair pathways to evolve, is the direct reversal of premutagenic lesions caused by ultraviolet (UV) irradiation, catalyzed by photolyases in a light-dependent, single-enzyme reaction. It has been experimentally shown that photoreactivation prevents UV mutagen...

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Bibliografiske detaljer
Main Authors: Lucas-Lledó, José Ignacio, Lynch, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668831/
https://ncbi.nlm.nih.gov/pubmed/19228922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msp029
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