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Chronic Granulomatous Disease: The European Experience
CGD is an immunodeficiency caused by deletions or mutations in genes that encode subunits of the leukocyte NADPH oxidase complex. Normally, assembly of the NADPH oxidase complex in phagosomes of certain phagocytic cells leads to a “respiratory burst”, essential for the clearance of phagocytosed micr...
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Main Authors: | , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668749/ https://ncbi.nlm.nih.gov/pubmed/19381301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005234 |
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