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Rac1 Is a Critical Mediator of Endothelium-Derived Neurotrophic Activity

The therapeutic potential of neurotrophic factors has been hampered by their inability to achieve adequate tissue penetration. Brain blood vessels, however, could be an alternative target for neuro-salvage therapies by virtue of their close proximity to neurons. Here we show that hemizygous deletion...

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Hlavní autoři: Sawada, Naoki, Kim, Hyung-Hwan, Moskowitz, Michael A., Liao, James K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668716/
https://ncbi.nlm.nih.gov/pubmed/19278959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000162
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