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Rac1 Is a Critical Mediator of Endothelium-Derived Neurotrophic Activity
The therapeutic potential of neurotrophic factors has been hampered by their inability to achieve adequate tissue penetration. Brain blood vessels, however, could be an alternative target for neuro-salvage therapies by virtue of their close proximity to neurons. Here we show that hemizygous deletion...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668716/ https://ncbi.nlm.nih.gov/pubmed/19278959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000162 |
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