Heterogeneity of ubiquitin pathology in frontotemporal lobar degeneration: classification and relation to clinical phenotype

We have investigated the extent and pattern of immunostaining for ubiquitin protein (UBQ) in 60 patients with frontotemporal lobar degeneration (FTLD) with ubiquitin-positive, tau-negative inclusions (FTLD-U), 37 of whom were ascertained in Manchester UK and 23 in Newcastle-Upon-Tyne, UK. There were...

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Autori principali: Mackenzie, Ian R. A., Baborie, Atik, Pickering-Brown, Stuart, Plessis, Daniel Du, Jaros, Evelyn, Perry, Robert H., Neary, David, Snowden, Julie S., Mann, David M. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2006
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668618/
https://ncbi.nlm.nih.gov/pubmed/17021754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-006-0138-9
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