Human Immunodeficiency Virus Integrates Directly into Naïve Resting CD4(+) T Cells but Enters Naïve Cells Less Efficiently than Memory Cells

Resting CD4(+) T cells restrict human immunodeficiency virus (HIV) infection at or before reverse transcription, resulting in slower kinetics of reverse transcription. In a previous study, we showed that, despite this restriction at reverse transcription, HIV integration occurs in resting CD4(+) T c...

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Détails bibliographiques
Auteurs principaux: Dai, Jihong, Agosto, Luis M., Baytop, Clifford, Yu, Jianqing J., Pace, Matthew J., Liszewski, Megan K., O'Doherty, Una
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668451/
https://ncbi.nlm.nih.gov/pubmed/19211752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01910-08
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