Borrelia burgdorferi bba74 Is Expressed Exclusively during Tick Feeding and Is Regulated by Both Arthropod- and Mammalian Host-Specific Signals

Although BBA74 initially was described as a 28-kDa virulence-associated outer-membrane-spanning protein with porin-like function, subsequent studies revealed that it is periplasmic and downregulated in mammalian host-adapted spirochetes. To further elucidate the role of this protein in the Borrelia...

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Main Authors: Mulay, Vishwaroop B., Caimano, Melissa J., Iyer, Radha, Dunham-Ems, Star, Liveris, Dionysios, Petzke, Mary M., Schwartz, Ira, Radolf, Justin D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Molecular Biology of Pathogens
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668432/
https://ncbi.nlm.nih.gov/pubmed/19218390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01802-08
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