A Role for a CXCR2/Phosphatidylinositol 3-Kinase γ Signaling Axis in Acute and Chronic Vascular Permeability

Most proangiogenic polypeptide growth factors and chemokines enhance vascular permeability, including vascular endothelial growth factor (VEGF), the main target for anti-angiogenic-based therapies, and interleukin-8 (IL-8), a potent proinflammatory mediator. Here, we show that in endothelial cells I...

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Detalhes bibliográficos
Main Authors: Gavard, Julie, Hou, Xu, Qu, Yi, Masedunskas, Andrius, Martin, Daniel, Weigert, Roberto, Li, Xuri, Gutkind, J. Silvio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668372/
https://ncbi.nlm.nih.gov/pubmed/19255141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01304-08
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