Recombinant Vesicular Stomatitis Virus Expressing Influenza Nucleoprotein Induces CD8 T-Cell Responses That Enhance Antibody-Mediated Protection after Lethal Challenge with Influenza Virus

Live attenuated vaccine vectors based on recombinant vesicular stomatitis viruses (rVSVs) expressing foreign antigens are highly effective vaccines in animal models. In this study, we report that an rVSV expressing influenza nucleoprotein (VSV NP) from the first position of the VSV genome induces ro...

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Hlavní autoři: Barefoot, Brice E., Sample, Christopher J., Ramsburg, Elizabeth A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Vaccine Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668267/
https://ncbi.nlm.nih.gov/pubmed/19244472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00451-08
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