Amifostine Induces Anti-Oxidant Enzymatic Activities in Normal Tissues and a Transplantable Tumor That Can Affect Radiation Response

PURPOSE: The purpose of this study is to determine whether amifostine can induce elevated manganese superoxide dismutase (SOD2) in mouse tissues and a transplantable SA-NH tumor resulting in a delayed tumor cell radioprotective effect. METHODS AND MATERIALS: SA-NH tumor-bearing C3H mice were treated...

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Bibliographic Details
Main Authors: Grdina, David J., Murley, Jeffrey S., Kataoka, Yasushi, Baker, Kenneth L., Kunnavakkam, Rangesh, Coleman, Mitchell C., Spitz, Douglas R.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668222/
https://ncbi.nlm.nih.gov/pubmed/19215822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2008.10.061
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