Quantitative Proteomics Reveals the Function of Unconventional Ubiquitin Chains in Proteasomal Degradation

All seven lysine residues in ubiquitin contribute to the synthesis of polyubiquitin chains on protein substrates. Whereas K48-linked chains are well established as mediators of proteasomal degradation, and K63-linked chains act in nonproteolytic events, the roles of unconventional polyubiquitin chai...

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Autores principales: Xu, Ping, Duong, Duc M., Seyfried, Nicholas T., Cheng, Dongmei, Xie, Yang, Robert, Jessica, Rush, John, Hochstrasser, Mark, Finley, Daniel, Peng, Junmin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668214/
https://ncbi.nlm.nih.gov/pubmed/19345192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.01.041
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