Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE

Alzheimer's disease (AD) is a genetically complex and heterogeneous disorder. To date four genes have been established to either cause early-onset autosomal-dominant AD (APP, PSEN1, and PSEN2(1–4)) or to increase susceptibility for late-onset AD (APOE(5)). However, the heritability of late-onse...

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Hlavní autoři: Bertram, Lars, Lange, Christoph, Mullin, Kristina, Parkinson, Michele, Hsiao, Monica, Hogan, Meghan F., Schjeide, Brit M.M., Hooli, Basavaraj, DiVito, Jason, Ionita, Iuliana, Jiang, Hongyu, Laird, Nan, Moscarillo, Thomas, Ohlsen, Kari L., Elliott, Kathryn, Wang, Xin, Hu-Lince, Diane, Ryder, Marie, Murphy, Amy, Wagner, Steven L., Blacker, Deborah, Becker, K. David, Tanzi, Rudolph E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668052/
https://ncbi.nlm.nih.gov/pubmed/18976728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.10.008
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