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Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease

Previous genome-wide association (GWA) studies typically focus on single-locus analysis, which may not have the power to detect the majority of genuinely associated loci. Here, we applied pathway analysis using Affymetrix SNP genotype data from the Wellcome Trust Case Control Consortium (WTCCC) and...

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Detalhes bibliográficos
Main Authors: Wang, Kai, Zhang, Haitao, Kugathasan, Subra, Annese, Vito, Bradfield, Jonathan P., Russell, Richard K., Sleiman, Patrick M.A., Imielinski, Marcin, Glessner, Joseph, Hou, Cuiping, Wilson, David C., Walters, Thomas, Kim, Cecilia, Frackelton, Edward C., Lionetti, Paolo, Barabino, Arrigo, Van Limbergen, Johan, Guthery, Stephen, Denson, Lee, Piccoli, David, Li, Mingyao, Dubinsky, Marla, Silverberg, Mark, Griffiths, Anne, Grant, Struan F.A., Satsangi, Jack, Baldassano, Robert, Hakonarson, Hakon
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668006/
https://ncbi.nlm.nih.gov/pubmed/19249008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2009.01.026
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