ISC1-dependent Metabolic Adaptation Reveals an Indispensable Role for Mitochondria in Induction of Nuclear Genes during the Diauxic Shift in Saccharomyces cerevisiae

Growth of Saccharomyces cerevisiae following glucose depletion (the diauxic shift) depends on a profound metabolic adaptation accompanied by a global reprogramming of gene expression. In this study, we provide evidence for a heretofore unsuspected role for Isc1p in mediating this reprogramming. Init...

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Main Authors: Kitagaki, Hiroshi, Cowart, L. Ashley, Matmati, Nabil, Montefusco, David, Gandy, Jason, de Avalos, Silvia Vaena, Novgorodov, Sergei A., Zheng, Jim, Obeid, Lina M., Hannun, Yusuf A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Metabolism and Bioenergetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667769/
https://ncbi.nlm.nih.gov/pubmed/19179331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805029200
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