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Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine

Covalent modification by methylation of cytosine residues represents an important epigenetic hallmark. While sequence analysis after bisulphite conversion allows correlative analyses with single-base resolution, functional analysis by interference with DNA methylation is less precise, due to the com...

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Autors principals: Baubec, Tuncay, Pecinka, Ales, Rozhon, Wilfried, Mittelsten Scheid, Ortrun
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667684/
https://ncbi.nlm.nih.gov/pubmed/18826433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-313X.2008.03699.x
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