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Mechanism of Constitutive Export from the Golgi: Bulk Flow via the Formation, Protrusion, and En Bloc Cleavage of large trans-Golgi Network Tubular Domains

Transport of constitutive cargo proteins from the Golgi complex to the plasma membrane (PM) is known to be mediated by large tubular-saccular carriers moving along microtubules. However, the process by which these large structures emerge from the trans-Golgi network (TGN) remains unclear. Here, we a...

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Main Authors: Polishchuk, Elena V., Di Pentima, Alessio, Luini, Alberto, Polishchuk, Roman S.
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Cell Biology 2003
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC266766/
https://ncbi.nlm.nih.gov/pubmed/12937271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-01-0033
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