Melan-A/MART-1(51–73) represents an immunogenic HLA-DR4-restricted epitope recognized by melanoma-reactive CD4(+) T cells

The human Melan-A/MART-1 gene encodes an HLA-A2-restricted peptide epitope recognized by melanoma-reactive CD8(+) cytotoxic T lymphocytes. Here we report that this gene also encodes at least one HLA-DR4-presented peptide recognized by CD4(+) T cells. The Melan-A/MART-1(51–73) peptide was able to ind...

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Dettagli Bibliografici

Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Zarour, Hassane M., Kirkwood, John M., Kierstead, Lisa Salvucci, Herr, Wolfgang, Brusic, Vladimir, Slingluff, Craig L., Sidney, John, Sette, Alessandro, Storkus, Walter J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2000
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26675/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10618430/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.1.400
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