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Decomposing complex reaction networks using random sampling, principal component analysis and basis rotation

BACKGROUND: Metabolism and its regulation constitute a large fraction of the molecular activity within cells. The control of cellular metabolic state is mediated by numerous molecular mechanisms, which in effect position the metabolic network flux state at specific locations within a mathematically-...

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Detalhes bibliográficos
Main Authors: Barrett, Christian L, Herrgard, Markus J, Palsson, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667477/
https://ncbi.nlm.nih.gov/pubmed/19267928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-3-30
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