Increased peripheral nerve excitability and local NaV1.8 mRNA up-regulation in painful neuropathy

BACKGROUND: Neuropathic pain caused by peripheral nerve injury is a chronic disorder that represents a significant clinical challenge because the pathological mechanisms have not been fully elucidated. Several studies have suggested the involvement of various sodium channels, including tetrodotoxin-...

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Autori principali: Thakor, Devang Kashyap, Lin, Audrey, Matsuka, Yoshizo, Meyer, Edward M, Ruangsri, Supanigar, Nishimura, Ichiro, Spigelman, Igor
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667430/
https://ncbi.nlm.nih.gov/pubmed/19320998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-5-14
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