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Biomechanical Thresholds Regulate Inflammation through the NF-κB Pathway: Experiments and Modeling

BACKGROUND: During normal physical activities cartilage experiences dynamic compressive forces that are essential to maintain cartilage integrity. However, at non-physiologic levels these signals can induce inflammation and initiate cartilage destruction. Here, by examining the pro-inflammatory sign...

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Detalhes bibliográficos
Main Authors: Nam, Jin, Aguda, Baltazar D., Rath, Bjoern, Agarwal, Sudha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667254/
https://ncbi.nlm.nih.gov/pubmed/19370157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005262
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