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Unc119 Protects from Shigella Infection by Inhibiting the Abl Family Kinases

BACKGROUND: Bacteria engage cell surface receptors and intracellular signaling molecules to enter the cell. Unc119 is an adaptor protein, which interacts with receptors and tyrosine kinases. Its role in bacterial invasion of cells is unknown. METHODOLOGY/PRINCIPAL FINDINGS: We used biochemical, mole...

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Detalhes bibliográficos
Main Authors: Vepachedu, Ramarao, Karim, Zunayet, Patel, Ojas, Goplen, Nicholas, Alam, Rafeul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667249/
https://ncbi.nlm.nih.gov/pubmed/19381274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005211
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