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Rapid repetitive element-mediated expansion of piRNA clusters in mammalian evolution

Piwi-interacting RNAs (piRNAs) are ≈30 nucleotide noncoding RNAs that may be involved in transposon silencing in mammalian germline cells. Most piRNA sequences are found in a small number of genomic regions referred to as clusters, which range from 1 to hundreds of kilobases. We studied the evolutio...

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Détails bibliographiques
Auteurs principaux: Assis, Raquel, Kondrashov, Alexey S.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667148/
https://ncbi.nlm.nih.gov/pubmed/19357307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900523106
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