A Structural Basis for the Regulatory Inactivation of DnaA

Regulatory inactivation of DnaA is dependent on Hda, a protein homologous to the AAA+ ATPase region of the replication initiator DnaA. When bound to the sliding clamp loaded onto duplex DNA, Hda can stimulate the transformation of active DnaA-ATP into inactive DnaA-ADP. The crystal structure of Hda...

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Detalhes bibliográficos
Main Authors: Xu, Qingping, McMullan, Daniel, Abdubek, Polat, Astakhova, Tamara, Carlton, Dennis, Chen, Connie, Chiu, Hsiu-Ju, Clayton, Thomas, Das, Debanu, Deller, Marc C., Duan, Lian, Elsliger, Marc-Andre, Feuerhelm, Julie, Hale, Joanna, Han, Gye Won, Jaroszewski, Lukasz, Jin, Kevin K., Johnson, Hope A., Klock, Heath E., Knuth, Mark W., Kozbial, Piotr, Krishna, S. Sri, Kumar, Abhinav, Marciano, David, Miller, Mitchell D., Morse, Andrew T., Nigoghossian, Edward, Nopakun, Amanda, Okach, Linda, Oommachen, Silvya, Paulsen, Jessica, Puckett, Christina, Reyes, Ron, Rife, Christopher L., Sefcovic, Natasha, Trame, Christine, van den Bedem, Henry, Weekes, Dana, Hodgson, Keith O., Wooley, John, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667141/
https://ncbi.nlm.nih.gov/pubmed/19000695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.10.059
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