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A Mycobacterium tuberculosis ligand-binding Mn/Fe protein reveals a new cofactor in a remodeled R2-protein scaffold

Chlamydia trachomatis R2c is the prototype for a recently discovered group of ribonucleotide reductase R2 proteins that use a heterodinuclear Mn/Fe redox cofactor for radical generation and storage. Here, we show that the Mycobacterium tuberculosis protein Rv0233, an R2 homologue and a potential vir...

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Detalhes bibliográficos
Main Authors: Andersson, Charlotta S., Högbom, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667070/
https://ncbi.nlm.nih.gov/pubmed/19321420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812971106
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