Lovastatin Potentiates the Antidepressant Efficacy of Fluoxetine in Rats

BACKGROUND: Cholesterol may have a role in the pathophysiology of depression. Lowering cholesterol levels with statins reduces risks for cardiovascular events, and there is clinical evidence that statins exert neuroprotective properties not fully explained by their effects on serum cholesterol level...

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Main Authors: Renshaw, Perry F., Parsegian, Aram, Yang, C. Kevin, Novero, Aileen, Yoon, Sujung J., Lyoo, In Kyoon, Cohen, Bruce M., Carlezon, William A.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666925/
https://ncbi.nlm.nih.gov/pubmed/19026674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.10.017
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