Use of Penalized Splines in Extended Cox-Type Additive Hazard Regression to Flexibly Estimate the Effect of Time-varying Serum Uric Acid on Risk of Cancer Incidence: A Prospective, Population-Based Study in 78,850 Men

PURPOSE: We sough to investigate the effect of serum uric acid (SUA) levels on risk of cancer incidence in men and to flexibly determine the shape of this association by using a novel analytical approach. METHODS: A population-based cohort of 78,850 Austrian men who received 264,347 serial SUA measu...

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Main Authors: Strasak, Alexander M., Lang, Stefan, Kneib, Thomas, Brant, Larry J., Klenk, Jochen, Hilbe, Wolfgang, Oberaigner, Willi, Ruttmann, Elfriede, Kaltenbach, Lalit, Concin, Hans, Diem, Günter, Pfeiffer, Karl P., Ulmer, Hanno
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666912/
https://ncbi.nlm.nih.gov/pubmed/18835524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.annepidem.2008.08.009
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