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Transcriptional Regulation of SM22α by Wnt3a: Convergence with TGFβ(1)/Smad Signaling at a Novel Regulatory Element
The role of canonical Wnt signaling in myofibroblast biology has not been fully investigated. The C3H10T1/2 mesenchymal cell line recapitulates myofibroblast differentiation in vitro and in vivo, including SM22α expression. Using this model, we find that Wnt3a upregulates SM22α in concert with TGFβ(...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666882/ https://ncbi.nlm.nih.gov/pubmed/19344627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.01.005 |
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