Highly efficient electro-gene therapy of solid tumor by using an expression plasmid for the herpes simplex virus thymidine kinase gene

We report successful electro-gene therapy (EGT) by using plasmid DNA for tumor-bearing mice. Subcutaneously inoculated CT26 tumor was subjected to EGT, which consists of intratumoral injection of a naked plasmid encoding a marker gene or a therapeutic gene, followed by in vivo electroporation (EP)....

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Détails bibliographiques
Auteurs principaux: Goto, Tomoaki, Nishi, Toru, Tamura, Takahiko, Dev, Sukhendu B., Takeshima, Hideo, Kochi, Masato, Yoshizato, Kimio, Kuratsu, Jun-ichi, Sakata, Tsuneaki, Hofmann, Gunter A., Ushio, Yukitaka
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2000
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC26667/
https://ncbi.nlm.nih.gov/pubmed/10618422
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