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Does intra-individual major histocompatibility complex diversity keep a golden mean?

An adaptive immune response is usually initiated only if a major histocompatibility complex (MHC) molecule presents pathogen-derived peptides to T-cells. Every MHC molecule can present only peptides that match its peptide-binding groove. Thus, it seems advantageous for an individual to express many...

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Detalhes bibliográficos
Main Authors: Woelfing, Benno, Traulsen, Arne, Milinski, Manfred, Boehm, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666699/
https://ncbi.nlm.nih.gov/pubmed/18926972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2008.0174
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