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A novel mechanism of late gene silencing drives Simian virus 40 transformation of human mesothelial cells
Suppression of the late gene expression, usually by integration of the viral DNA into the host genome, is a critical step in DNA tumor viruses carcinogenesis. Simian virus 40 (SV40) induces high rates of transformation in infected primary human mesothelial cells (S-HM) in tissue culture, leading to...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666620/ https://ncbi.nlm.nih.gov/pubmed/19010924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2332 |
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