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Krüppel-like Factor 5 Shows Proliferation-specific Roles in Vascular Remodeling, Direct Stimulation of Cell Growth, and Inhibition of Apoptosis

Krüppel-like factor 5 (KLF5), originally isolated as a regulator of phenotypic modulation of vascular smooth muscle cells, induces pathological cell growth and is expressed in the neointima. Although induction of KLF5 up-regulates growth factors like platelet-derived growth factor-A chain, how KLF5...

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Autori principali: Suzuki, Toru, Sawaki, Daigo, Aizawa, Kenichi, Munemasa, Yoshiko, Matsumura, Takayoshi, Ishida, Junichi, Nagai, Ryozo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666607/
https://ncbi.nlm.nih.gov/pubmed/19189969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806230200
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