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Mammalian Heat Shock Factor 1 Is Essential for Oocyte Meiosis and Directly Regulates Hsp90α Expression

Heat shock transcription factor 1 (HSF1) is the main regulator of the stress response that triggers the transcription of several genes encoding heat shock proteins (Hsps). Hsps act as molecular chaperones involved in protein folding, stability, and trafficking. HSF1 is highly expressed in oocytes an...

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Detalhes bibliográficos
Main Authors: Metchat, Aïcha, Åkerfelt, Malin, Bierkamp, Christiane, Delsinne, Virginie, Sistonen, Lea, Alexandre, Henri, Christians, Elisabeth S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666604/
https://ncbi.nlm.nih.gov/pubmed/19158073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808819200
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