RGC-32 Mediates Transforming Growth Factor-β-induced Epithelial-Mesenchymal Transition in Human Renal Proximal Tubular Cells

Epithelial-mesenchymal transition (EMT) occurs in several disease states, including renal fibrosis and carcinogenesis. Myofibroblasts produced from EMT of renal tubular cells are responsible for the deposition of extracellular matrix components in a large portion of renal interstitial fibrosis. Tran...

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Autors principals: Huang, Wen-Yan, Li, Zu-Guo, Rus, Horea, Wang, Xiaoyan, Jose, Pedro A., Chen, Shi-You
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Molecular Basis of Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666595/
https://ncbi.nlm.nih.gov/pubmed/19158077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900039200
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