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A Common Biosynthetic Pathway Governs the Dimerization and Secretion of Inhibin and Related Transforming Growth Factor β (TGFβ) Ligands

The assembly and secretion of transforming growth factor β superfamily ligands is dependent upon non-covalent interactions between their pro- and mature domains. Despite the importance of this interaction, little is known regarding the underlying regulatory mechanisms. In this study, the binding int...

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Main Authors: Walton, Kelly L., Makanji, Yogeshwar, Wilce, Matthew C., Chan, Karen L., Robertson, David M., Harrison, Craig A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666583/
https://ncbi.nlm.nih.gov/pubmed/19193648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808763200
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