Cold Adaptation of Zinc Metalloproteases in the Thermolysin Family from Deep Sea and Arctic Sea Ice Bacteria Revealed by Catalytic and Structural Properties and Molecular Dynamics: NEW INSIGHTS INTO RELATIONSHIP BETWEEN CONFORMATIONAL FLEXIBILITY AND HYDROGEN BONDING

Increased conformational flexibility is the prevailing explanation for the high catalytic efficiency of cold-adapted enzymes at low temperatures. However, less is known about the structural determinants of flexibility. We reported two novel cold-adapted zinc metalloproteases in the thermolysin famil...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Xie, Bin-Bin, Bian, Fei, Chen, Xiu-Lan, He, Hai-Lun, Guo, Jun, Gao, Xiang, Zeng, Yin-Xin, Chen, Bo, Zhou, Bai-Cheng, Zhang, Yu-Zhong
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Protein Structure and Folding
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666578/
https://ncbi.nlm.nih.gov/pubmed/19181663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808421200
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares