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A Novel Method for Detection of Phosphorylation in Single Cells by Surface Enhanced Raman Scattering (SERS) using Composite Organic-Inorganic Nanoparticles (COINs)

BACKGROUND: Detection of single cell epitopes has been a mainstay of immunophenotyping for over three decades, primarily using fluorescence techniques for quantitation. Fluorescence has broad overlapping spectra, limiting multiplexing abilities. METHODOLOGY/PRINCIPAL FINDINGS: To expand upon current...

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Detalhes bibliográficos
Main Authors: Shachaf, Catherine M., Elchuri, Sailaja V., Koh, Ai Leen, Zhu, Jing, Nguyen, Lienchi N., Mitchell, Dennis J., Zhang, Jingwu, Swartz, Kenneth B., Sun, Lei, Chan, Selena, Sinclair, Robert, Nolan, Garry P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666268/
https://ncbi.nlm.nih.gov/pubmed/19367337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005206
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