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High levels of retinal membrane docosahexaenoic acid increase susceptibility to stress-induced degeneration
The fat-1 gene cloned from C. elegans encodes an n-3 fatty acid desaturase that converts n-6 to n-3 PUFA. Mice carrying the fat-1 transgene and wild-type controls were fed an n-3-deficient/n-6-enriched diet [fat-1- safflower oil (SFO) and wt-SFO, respectively]. Fatty acid profiles of rod outer segme...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666167/ https://ncbi.nlm.nih.gov/pubmed/19023138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800170-JLR200 |
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